Gene Test Predicts Melanoma Metastases

DENVER — A diagnostic test that uses gene-expression profiles can help establish which primary cutaneous melanoma tumors are likely to metastasize, a new study shows.

This could help identify patients who could then be put on a more aggressive screening schedule, and perhaps even be given adjuvant therapies such as immune-modulating agents, said Pedram Gerami, MD, associate professor of dermatology and pathology and director of melanoma research at the Northwestern Skin Cancer Institute in Chicago.

Molecular diagnostics have begun to change prognostication in other tumors, and “people in the melanoma field are realizing that the time is right for it here, as well,” he said.

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